A potential drug target for itching sensations has been developed by researchers. Their work shows that skin cells -- when exposed to certain itch-producing chemicals -- can powerfully regulate nearby sensory nerve cells and facilitate transmission of the itchy feelings to the brain. The ion channel TRPV4 functions in skin cells as a pivotal switch in this newly revealed signaling pathway.
A potential drug target for itching sensations has been developed by researchers. Their work shows that skin cells -- when exposed to certain itch-producing chemicals -- can powerfully regulate nearby sensory nerve cells and facilitate transmission of the itchy feelings to the brain. The ion channel TRPV4 functions in skin cells as a pivotal switch in this newly revealed signaling pathway.
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